| Sanborn | From The Sandy Brook | Male |
| Saunderson | Alexander's Son | Male |
| Sawyer | Cuts Timber | Male |
| Saxon | Sword | Male |
| Scarlet | Red | Female |
| Scarlett | Red | Female |
| Scott | From Scotland | Male |
| Seabert | Glory At Sea | Male |
| Seabrook | From The Brook By The Sea | Male |
| Sealey | From The Happy Meadow | Male |
| Seger | Seaman | Male |
| Shandy | Variant Of Shaun From John. | Male |
| Shelby | Sheltered Town | Female |
| Sheldon | From The Shield Farm | Male |
| Shelley | From The Ledge Meadow | Male |
| Shelly | From The Ledge Meadow | Female |
| Shelton | From The Ledge Farm Deep Valley. | Male |
| Shepherd | Shepherd | Male |
| Sherborne | From The Clear Brook | Male |
| Sherman | Cuts The Nap Of Woolen Cloth. Shireman In Medieval Times The Shireman Served As Governor-Judge Of An English Shire Or County. | Male |
| Sherwin | Quick As The Wind | Male |
| Sherwood | From The Bright Forest | Male |
| Shirley | From The White Meadow | Female |
| Skylar | Phonetic Spelling Of Schuyler. | Male |
| Slade | From The Valley | Male |